Latest Heisman Odds & Predictions (2025)

The top QB prospects in college football this year headline the Heisman odds as the final month of the regular season kicks off. Who can lead their team to a playoff berth, and which player will take home the honor of being named the 2025 Heisman Trophy winner?

This guide highlights the updated Heisman Trophy odds. I discuss the current odds and break down the odds for the top contenders in this year’s Heisman race. Also, I provide my prediction for what is a wide-open race through 11 weeks.

Current 2025 Heisman Trophy Odds

Check out the table below to shop the latest Heisman Trophy winner odds, courtesy of Lucky Rebel. 

Sophomore QB Julian Sayin has led the Buckeyes to a 9-0 start to their title defense this year. Ohio State is the top-ranked team in the country, and Sayin is the +160 favorite in the current Heisman betting odds. 

Just behind Sayin is Fernando Mendoza at +175. Mendoza has guided Indiana to the second-best ranking in the sport. 

Alabama’s Ty Simpson is a distant third at +450 odds. Marcel Reed (Texas A&M) and Diego Pavia (Vanderbilt) round out the top five at +700 and +2000, respectively. 

WR Jeremiah Smith (+3300) and RB Jeremiyah Love (+3500) are in a close battle for the best odds of any non-quarterback. 

Lucky Rebel is the best place to make your Heisman winner bets. Check out our Lucky Rebel review to find out more about this highly-rated college sportsbook. 

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Why is Julian Sayin the 2025 Heisman Favorite?

A true freshman at the time. Julian Sayin watched from the bench as the Buckeyes won the National Championship last year. With Sayin under center to start Week 1, the Buckeyes opened at #3 in the AP Top 25. 

Sayin and Ohio State took down #1 Texas in the opener, reclaimed the top spot in the AP poll, and have not looked back since. 

Much of the Buckeyes’ success this year has been due to their dominant defense, which is allowing just 7.2 PPG to opposing teams. However, Sayin and the offense have also started to round into form. Ohio State has scored 34+ points in five straight games. 

The Heisman case for Sayin is easy: he is the QB on the best team in college football. If he can lead Ohio State to a Big Ten title and end the Buckeyes’ losing streak against Michigan, Sayin will win the Heisman.

2025 Heisman Trophy Sleepers

The regular season is winding down, but there is still plenty of time for Heisman hopefuls to make moves in a wide-open race. Here are two sleepers to watch in this year’s Heisman Trophy race. 

Fernando Mendoza (+175)

Indiana has risen to #2 in the AP poll, and it debuted at #2 in the CFP poll. The play of quarterback Fernando Mendoza has been a major part of the Hoosiers’ success this season. He has shot up Heisman odds boards at top college football betting sites as a result.  

Mendoza has completed 71.3% of his passes this season, the highest of his college career. The Junior has also racked up 2,342 passing yards at a rate of 9.2 YPA. Mendoza has a 26-5 TD:INT ratio this season.

Ty Simpson (+450)

After a rough loss in his debut as a starter, Ty Simpson has helped the Crimson Tide win eight straight games, include four consecutive wins against ranked opponents. He is listed at +450 in the latest Heisman Trophy betting odds. 

Simpson’s stats this season include:

• 2,461 passing yards
• 66.9% completion percentage
• 8.3 YPA
• 21 passing TDs
• 1 INT

He has led the Tide into the top four in AP poll, but Simpson still has plenty of work left to do. Alabama needs to win out and make the SEC title game for Simpson to have a shot at winning the Heisman this season.

Factors Driving Heisman Trophy Odds

Heisman voting can be a complicated process, but bettors must learn the ins-and-outs of the award to have a chance at winning their futures wagers. 

• 3-2-1 voting system: Each voter ranks their three top choices. First place votes get three points, second gets two, and third place votes are worth one point. 
• Best player on the best team: The Heisman is only awarded to one player, but team success is still a factor. Only one player, Notre Dame’s Paul Hornung (1956), has won the Heisman on a losing team.  
• Importance of position and conference: Offensive players, especially quarterbacks, have an inherent advantage when it comes to Heisman voting. Players in more respected conferences, like the SEC and Big Ten, also have an easier time earning respect from voters.
• Individual greatness: A player must prove their individual worth, too. Big plays in big games are exactly what a contender needs to create their “Heisman” moment.
• Season-long performance: Candidates for the Heisman can emerge at any time in the regular season. However, player who have a whole season‘s worth of great performances are more likely to win than candidates who are inconsistent throughout the year.

Heisman Trophy Betting Tips

Keep these three tips in mind when betting on your Heisman picks.

Past Heisman Trophy Winners

Who Will Win the 2025 Heisman Trophy Award?

• Fernando Mendoza (+175) – Bet now!

Fernando Mendoza, who is second in the latest Heisman odds, and the #2 Hoosiers have been the surprise of the college football season. Indiana is talented, but Mendoza does not have nearly the same level of talent around him as Julian Sayin or Ty Simpson. Succeeding despite a relatively lower level of skill players around him will be the key to Mendoza’s Heisman case. 

Keep up with the latest odds and bet on your Heisman trophy predictions at Lucky Rebel. New members can claim up to $1,250 in extra funds when they claim the site’s welcome bonus with their first deposit.