Top Week 4 NFL Prop Bets (2025)

There is no better way to wager on your favorite teams this week than with NFL prop bets. You can bet on specific players or bet on aspects of the games themselves.
Keep reading to see the best prop bets available in the NFL this week. I highlight my top NFL prop bets this week, breaking down my predictions for each wager. Also, I will give you specific tips to keep in mind when betting on Week 4 of the NFL season.
Top NFL Player Props for Week 4
Here are my favorite NFL player prop bets for Week 4, using the latest odds courtesy of Lucky Rebel Sportsbook.
Keenan Allen Anytime TD Scorer (+160)
Keenan Allen’s one-year stint in Chicago did not go as planned. Luckily for everyone involved, Allen is back in LA with the Chargers. He leads the team in targets (28) and receptions (19) through three games.
Allen also has three of the Chargers’ six receiving TDs this year. Quentin Johnston, who leads the team with 239 receiving yards, has caught Justin Herbert’s other three TD passes.
Lucky Rebel lists Allen at +160 odds to score his fourth touchdown of this season. Los Angeles takes on the New York Giants at MetLife this week.
The Giants have allowed 252 passing YPG, the fifth-most in the league this season, and four passing TDs. LA should have no problem moving the ball through the air this week, and Allen will find the endzone at least once on Sunday.
Jaylen Warren Over 82.5 Scrimmage Yards (-115)
The Steelers host the Vikings in Ireland this week in the first early kickoff of the season. Minnesota’s stout defense forced multiple turnovers last week, including two that were returned for touchdowns.
Aaron Rodgers is not as mobile as he used to be, so the 41-year-old will need to get rid of the ball quickly. Establishing their running game early will also help the Steelers slow down the Vikings’ pass rush.
Dump off passes and a heavy dose of rush attempts should help Jaylen Warren pad his stats this week. He is listed at over/under 82.5 scrimmage yards for Sunday’s game, and he will cover the over.
Warren leads the team in rushing (132) and receiving (142) yards this season and will receive more than enough touches on Sunday to get over 82.5 total yards.
Travis Etienne Over 67.5 Scrimmage Yards (-118)
Another running back I think will cover their scrimmage yards total this week is Jacksonville’s Travis Etienne. He is listed at over/under 67.5 rushing and receiving yards for this Sunday’s game against the 49ers.
Etienne’s 156 scrimmage yards in Week 1 gave the Jaguars enough confidence to trade his backup, Tanks Bigsby. That move may have been premature, as Etienne gained just 89 and 56 total scrimmage yards against Cincinnati and Houston, respectively.
Jacksonville takes on the 49ers in San Francisco. The 49ers have been ravaged by injuries on both sides of the ball. Despite their injuries, San Fran has only allowed 265.7 total YPG, the fourth-fewest in the NFL.
I believe the 49ers’ injuries will catch up with them this week, and Etienne will bounce back from his poor production last week. The talent dual-threat running back will have over 67.5 scrimmage yards against San Fran.
Jordan Love’s Longest Completion Over 38.5 yards (-115)
My final Week 4 player prop is for Jordan Love’s longest completion to be over 38.5 yards. Love and the Packers will face the Cowboys in Dallas on Sunday Night Football.
Dallas’s defense has struggled to generate a pass rush this season. Their ability to stop the pass has suffered greatly as a result. The Cowboys have allowed 288 passing YPG, the most of any team in the league.
Love and the Packers’ passing game have struggled at times to start the season. He will also be without his top two receivers, as Christian Watson and Jayden Reed are out for the foreseeable future.
On the bright side, Love has plenty of other young, talented receivers to work with. Green Bay’s passing attack will get back into rhythm this week, and Love will have at least one pass of over 38.5 yards.
Best Week 4 NFL Game Prop Bets
Football fans have exciting game props to bet on in Week 4. Here are my top game props for this weekend’s games.
Bills, Lions, and Chargers Each Score 25+ (+250)
The Bills, Lions, and Chargers have been three of the best scoring teams this season. Buffalo and Detroit are both averaging 34.0+ PPG this season. LA, on the hand, has scored at least 20 points in every game this year.
You can bet on all three teams to score at least 25 points this week at +250 odds.
Buffalo faces the Saints, who have allowed 30.0 PPG this year. LA takes on the Giants, who are allowing 27.7 PPG so far in 2025.
Detroit faces the toughest defense of the three in its matchup against Cleveland. The Browns have allowed 17 or fewer points in two of their three games this year. However, when they went to Baltimore, Cleveland allowed 41 points.
The Lions are at home and should be able to exploit the weak points in the Browns’ defense and score at least 25 points. Likewise, the Bills and Chargers will also get at least 25 points this week.
Detroit Lions Win Both Halves (+109)
Speaking of the Lions, I expect them to win both halves (+109) against Cleveland on Sunday.
The Browns did not win a half, let alone a game, until their 13-0 in the fourth quarter against Green Bay. Detroit’s offense has rolled the last two weeks, combining for 90 points over the latest eight quarters.
For comparison, Cleveland has scored a total of 46 points this season, the third-fewest in the NFL. Detroit will not score 38+ on Cleveland, but they should easily win both halves against a Browns’ offense that is allergic to scoring.
Buccaneers Win and Both Teams Score 20+ points (+450)
The Buccaneers welcome the defending champion Eagles this weekend in a battle of 3-0 teams. Tampa Bay is an underdog, but they have beaten the Eagles in four of their last five matchups.
Philly and Tampa Bay are averaging 25.7 and 24.0 PPG this year, respectively. They have also both scored at least 20 points in every game this year.
A Bucs’ upset with both teams scoring at least 20 points pays +450 in this NFL game prop. Both teams’ offenses are good enough to top 20 points for the fourth straight week, and Baker Mayfield is 3-for-3 on game-winning drives this season.
Ravens – Chiefs – REG (+900)
Rounding out my top NFL bets for Week 4 is this first-half final-result game prop for Baltimore vs. Kansas City. For this bet to win, the Ravens must win the first half, but the Chiefs need to come back in the second half and win the game in regulation.
I picked the Chiefs in my Week 3 NFL props, and I am riding with them again this week.
Both teams are 1-2, but they have gotten there in different ways. Baltimore should be 3-0, but their offense has stalled out in the second half of their two losses this season. Kansas City, on the other hand, struggled to find its mojo at the start of the season.
The Ravens’ explosive offense should give them an early lead again. However, when they inevitably choke again in the second half, Patrick Mahomes will lead another comeback win and improve to 6-1 against Lamar Jackson.
Week 4 NFL Prop Betting Trends and Tips
The first month of the season is almost over, and there have been many surprises thus far. Here are some trends and tips to consider that can help you stay ahead of other bettors this week at top NFL betting sites.
Travel, Start Times, and Short Weeks
Fatigue will gradually become a more significant factor as the season progresses. Teams that must travel long distances or play on short weeks typically perform worse. This is especially relevant in Week 4 as the NFL kicks off its European slate of games with the Vikings facing the Steelers in Ireland.
Watch for Changes to Starting Lineups
Injuries, poor performances, and job insecurity lead to changes in starting lineups every season. The injury bug has already bitten several teams, and Russell Wilson has been benched for his poor play. Tracking lineup changes can help you identify value before other bettors.
Where to Bet on NFL Week 4 Props
There is no place better for wagering on NFL prop bets this week than Lucky Rebel. It offers hundreds of player and game props for every Week 4 matchup. You can even wager on my favorite prop of the week: Keenan Allen anytime TD scorer (+160).
Lucky Rebel also offers an exciting welcome bonus for new members. If you create a new account today, you can claim a 125% match on your first qualifying deposit.