Latest 2025 NFL Thanksgiving Day Odds

The 2025 NFL Thanksgiving Day odds are loaded with exciting betting options. Green Bay takes on Detroit, the Cowboys host the Chiefs, and Cincinnati heads to Baltimore. 

This guide highlights the latest NFL Thanksgiving 2025 game odds. I will analyze the updated odds for this year’s Thanksgiving games and break down my updated predictions for each game. 

Odds for 2025 NFL Thanksgiving Games

Here are the latest 2025 NFL Thanksgiving game odds, courtesy of BetUS. 

Green Bay Packers vs. Detroit Lions 

Green Bay is a 3.0-point underdog against the Lions in Detroit on Thanksgiving. Both teams are chasing Chicago for the top spot in the NFC North, so there is plenty to play for in this divisional game. 

The Packers beat the Lions in Week 1, but Detroit has been the better team since then. In a tight NFC playoff race, the loser of this game could lose vital positioning in the Wild Card standings.  

Kansas City Chiefs vs. Dallas Cowboys

Dallas has scored 40+ points in three of its home games this season, and the Chiefs’ offense has struggled more often than not. Despite that, top NFL betting sites list the Chiefs as 4.5-point road favorites at Jerry World for this game. 

KC is doing its best to climb into the AFC playoff picture. A loss in this game could all but end the Chiefs’ season. 

Cincinnati Bengals vs. Baltimore Ravens

In prime time, the Bengals will take on the Ravens in Baltimore. This game will hinge on whether Joe Burrow can return to the starting lineup for the Bengals. 

Without Burrow, the Bengals have little to no chance to win as 7.5-point underdogs. Even if Burrow is back, the Bengals’ defense will need to step up its game to hang with the Ravens’ offense in this AFC North divisional matchup. 

Best Thanksgiving NFL Bets for 2025

• Green Bay Packers +3.0 (-120)
• Kansas City Chiefs -4.5 (-110)
• Cincinnati Bengals +7.5 (-115)

Green Bay dominated the Lions in Week 1, taking down Detroit 27-13 at Lambeau. The Packers’ offense has been inconsistent, but Green Bay’s defense is championship caliber. Micah Parsons and company will harass Jared Goff early and often, allowing the Packers to cover the 3.0-point spread. 

Kansas City has a long way to go to secure its spot in the postseason, including a tough Week 12 matchup. Dallas has a great offense, averaging nearly 40 PPG at home, but the Chiefs’ defense is better. The Cowboys have multiple losses by 10+ points this season, and KC should cover the 4.5 in this holiday matchup. 

The Bengals’ hopes of keeping their season alive without Joe Burrow crashed and burned. However, if Burrow is back, he should improve an already high-scoring offense. A Burrow-led Bengals team can cover +7.5 against Baltimore.

2025 NFL Predictions for Thanksgiving Day

• Green Bay Packers
• Kansas City Chiefs
• Baltimore Ravens

When kept upright, Jared Goff can be one of the best QBs in the NFL. However, Goff quickly turns into one of the worst QBs if he is pressured. The Packers D-Line will be the deciding factor, overpowering the Lions O-Line and leading Green Bay to a win. 

The Chiefs cannot afford to lose this game in Dallas. A motivated and desperate Patrick Mahomes will slice and dice a Cowboys defense that allows the third-most passing yards in the league. Mahomes and company will secure a vital win in Dallas on Turkey Day. 

Baltimore has been on a tear, running down an inconsistent Steelers team for first place in the AFC North. A win over division rival Cincinnati will do wonders for Baltimore’s hopes of securing the AFC North title. It might not be pretty, but the Ravens will win this prime-time game.  

Betting on NFL Thanksgiving Games in 2025

Wagering on the annual Thanksgiving game odds is the best way to make every matchup more exciting. You can bet on every Thanksgiving game at BetUS. 

BetUS is offering a 125% welcome bonus on your first three deposits to new members. This bonus promotion is a great way to grow your bankroll for these unique matchups on Turkey Day.