Wednesday’s MLB Predictions and Betting Tips (May 19, 2021)

| May 19, 2021 5:42 am PDT

An afternoon tilt in the Twin Cites kicks off a 15-game slate on Wednesday. The White Sox look to grow their case as the best team in the league in a matchup against a team with the least number of wins.

The Dodgers square off with the D-Backs in hopes of staying within an arm’s length of the Giants and Padres in the NL West standings. Fortunately for Dave Roberts, Clayton Kershaw is on the mound aiming to become the second 7-win pitcher in baseball. However, by the time Kershaw takes the bump in Los Angeles, Jack Flaherty could be in the process of wrapping up his league-leading eighth victory.

With a full schedule on tap, let’s start diving into today’s MLB predictions.

MLB Game Winner Predictions for May 19th  

  • White Sox to beat the Twins
  • Padres to beat the Rockies
  • Giants to beat the Reds
  • Marlins to beat the Phillies
  • Orioles to beat the Rays
  • Mets to beat the Braves
  • Red Sox  to beat the Blue Jays
  • Nationals to beat the Cubs
  • Cardinals to beat the Pirates
  • Rangers to beat the Yankees
  • Angels to beat the Indians
  • Brewers to beat the Royals
  • Athletics to beat the Astros
  • Dodgers to beat the Diamondbacks
  • Tigers to beat the Mariners

Lucas Giolito is hoping to get on track today versus the Twins. It’s been tough sledding thus far for the guy who was expected to be Chicago’s ace – Giolito is sporting a 4.97 ERA, and the White Sox have lost six of the eight games he’s started.

I like the Padres to beat the Rockies, but not at the -235 price tag installed at the safest betting sites. I’ll be hopping on John Means coattails in Baltimore – the only reason it’s not showcased below is because odds for the Rays vs. Orioles game hadn’t been released at the time of this writing.

In any case, lock the O’s in as one of the best MLB picks on Wednesday, and don’t look back.

Top MLB Upset Picks for May 19th

  • Marlins +118 (over the Phillies)
  • Red Sox +110 (over the Blue Jays)

Zach Eflin has done a commendable job for the Phillies in 2021. His 51/5 K/BB ratio is outstanding, as is the fact that he’s logged at least six innings in each of his eight starts. Having said that, Eflin has yielded 55 hits (2nd most in the majors) and allowed five runs in his most recent outing.

Rather than contemplate betting on Philly at -128, I’m intrigued by the Marlins at +118.

After getting his feet wet with seven starts in 2020, Trevor Rogers is quietly turning into a beast of a left-handed pitcher. The 6’5” southpaw is 5-2 with a 1.84 ERA. He’s given up just four hits and one run in back-to-back starts.

Without a whole lot of appetizing upset picks on the board on Wednesday, I’ll be keeping close tabs on the NL East battle in Philadelphia.

Over in the AL East, I’ll admit that I’m actively looking to fade Ross Stripling anytime he takes the mound.

Stripling (0-2, 5.91 ERA) rocked a disastrous 1.596 WHIP last year and has somehow plummeted even further in 2021 (1.688 WHIP).

Boston SP Garrett Richards (3-2, 3.89 ERA) has looked terrific in three of his last four outings. In the only instance he struggled, the Red Sox still won by five runs.

For what it’s worth, the Red Sox own the best-winning % in the league as a road underdog (.833).

Best MLB Bets for Wednesday, May 19th 

  • Giants over the Reds (-113)
  • Brewers over the Royals (-155)

So much for any positive carryover from Wade Miley’s no-hitter. 11 hits and 8 runs in just three innings last time out versus the Rockies – it’s safe to say that the hulk sticker applied on Wade’s forearm sincerely wore off, which brings me to my next point.

While Miley was busy getting shelled last Friday, his adversary in today’s matchup was wheeling and dealing.

Kevin Gausman’s Last Start – 5/14 against the Pirates
Innings Hits Earned Runs Strikeouts Walks
8.0 5 1 12 0

That’s now five straight appearances surrendering zero or one run for Gausman. He’s struck out 36 and walked just three batters during that stretch.

Between the glaring discrepancies in the pitching matchup and the Giants having a significantly better record, I wouldn’t have batted an eye had San Fran been listed at -150. Consider “-113” an extreme bargain.

The last of the MLB picks on May 19th I’m endorsing is probably the easiest selection of all. At least on paper, anyway. One can argue that the batting Brewers and Royals batting orders are on a level playing field. What can’t be denied is how lopsided the pitching duel is.

On the one hand, we have Corbin Burnes – a dude with an unheard of 0.641 WHIP and a blistering 1.57 ERA. Coming off a dominant season in 2020, you can’t have a conversation about the best pitchers in the game without referencing Burnes’ name.

On the flip side, the Royals are leaning on Brad Keller. Instead of using adjectives to describe the disparity between Keller and Burnes, I’ll let the graphic below do all the talking for me.

Corbin Burnes vs. Brad Keller – By the Numbers
Starts Innings Hits Earned Runs Strikeouts Walks
Corbin Burnes 6 34.1 21 6 58 1
Brad Keller 8 33.1 46 25 29 16

I’m assuming by now that you’re onboard backing the Brewers. If you need more convincing, know that the Royals are 3-7 as a home underdog.

Michael Wynn
Michael Wynn

As a former Division I collegiate golfer, Michael Wynn loves writing about golf. He's also an expert in most of America's most popular sports, writing extensively for GamblingSites.com on football, basketball, and baseball.

Michael's a Las Vegas native and has been with the company since 2017.

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