MMA DFS Picks and Top Lineup for UFC Vegas 43 – November 20, 2021

| November 19, 2021 1:58 pm PDT

The comeback trail rages on for Miesha Tate, but is she among the best UFC Vegas 43 DFS picks for this weekend?

A lot of MMA fans will hope so. Tate scored a TKO win in her return from a five-year retirement, and it would be truly special if she could work her way to a title.

Tate joins Ketlen Vieira for this week’s main event at UFC Vegas 43, but they aren’t the only fighters to consider. You need more than them to fill out your MMA DFS lineups, after all.

Last week’s MMA DFS picks were a mixed bag. Max Holloway, Felicia Spencer, and Joel Alvarez all scored wins. I was more helpful in the betting realm, though, as two of my bets converted.

A new week of fighting is here, though.

Let’s see where fighters from the main event slide in – and who else you should prioritize – in my UFC Vegas 43 DFS preview.

Top UFC Vegas 43 DFS Picks

I will admit that I walked into my UFC Vegas 43 DFS picks with extreme bias. How can you not most weeks, but seriously, I want Tate to rise to the top. It’s just such a great story.

Could that impact how I go about things this week? Perhaps. Regardless, let’s go over the three fighters I want to build around.

Miesha Tate ($8.3k)

I’ll start things off with the seasoned Tate, who did what she had to to get a win in her first fight back. Since then, she dealt with a battle with COVID-19, which delayed this showdown with Ketlen Vieira the first time around.

There is valid concern as to just how much the virus impacted Tate, and if it’ll play into this fight. I doubt she’d move forward unless she felt completely ready, however.

Tate came back with a title shot on the brain, and winning a main event like this would launch her back into the conversation.

It didn’t work out the last time, but Tate has her sights set on taking out Amanda Nunes.

The 35-year old is as battle tested and versatile as they come, and this just feels like a mismatch.

The booster? Tate is coming in at lower ownership, and yet these two see their fantasy point projection separated by 0.1 at

Michael Chiesa ($7.3k)

Tate is a fun play due to the ownership, projection, and narrative. I’ll go hard after Michael Chiesa, who feels like an elite value.

This is a showdown between two grapplers, but Chiesa is the more balanced fighter and the more dangerous striker.

He’s coming over a very understandable defeat to Vicente Luque, and as tough as it is, this looks like a bounce-back spot for him. Chiesa certainly isn’t coming in with a lack of focus.

“I just want to prove that I’m still that guy. There’s no better way to do that than fighting the tough, undefeated, up-and-coming [Brad].” Michael Chiesa on fight with Brady

Chiesa knows what’s in front of him. He can use his superior striking to get to Brady, and his elite ground work (11 career submissions) could come into play.

Brady is a tough out. He’s undefeated for a reason. But most fighters taste defeat at some point, and a loss to Chiesa would hardly be damaging. This fight means more to Chiesa at this point, and I can’t get away from his price tag.

Adrian Yanez ($9.1k)

Lastly, I’ll take all of the Adrian Yanez – please and thank you.

Few fighters call to you on this card, but Yanez is a first round finish waiting to happen. He comes in with a stout 14-3 record, winning nine fights by KO.

He’s done that in each of his first three UFC bouts, while seven of his last nine fights have ended by early stoppage with his fists.

It all started with the Contender Series, and Yanez hasn’t looked back since.

The kid is insanely dangerous on his feet, and he’s the quicker fighter compared to this week’s opponent, Davey Grant.

Yanez is just the superior striker here, and I think youth and speed win out. He’s also simply a rising star, whereas the 35-year old Grant is understandably trending in the opposite direction.

My Favorite UFC Vegas 43 DFS Lineup

  • Miesha Tate ($8.3k)
  • Michael Chiesa ($7.3k)
  • Adrian Yanez ($9.1k)
  • Pat Sabatini ($8.7k)
  • Rani Yahya ($8k)
  • Terrance McKinney ($8.4k)

Narrative Street has me digging the balanced Tate, I love the value with Chiesa, and I think Yanez is one of the safest locks of the night.

From there, we can slap Sabatini, Yahya, and McKinney on the board to round out this lineup.

Yahya is a bit long in the tooth, but he is elite on the floor. He has 21 submissions on his resume, and in 37 career fights, he’s tapped out just once. In a fight with similar styles, I think he has the edge.

There’s also Terrance McKinney, who is a nasty striker.

Just look at his last four fights – all KO wins within the first two minutes.

I’ll wrap things up with Sabatini, who is a rock solid fighter. He’s 15-3 overall, 2-0 in the UFC, and he is a boss on the ground.

Sabatini is one tough cookie, and he’s insanely crafty. I don’t think he’s an easy out for Tucker Lutz at all, and if the fight goes to the ground, he has the edge. He’s my last guy in, but I think he has a good shot at the win.

Betting Advice for UFC Fight Night: Vieira vs. Tate

I like the UFC Vegas 43 DFS lineup above, but there is also money to be made by betting on this fight card.

Not all of my MMA DFS picks will translate to the betting realm. Some of the pricing at the best UFC betting sites disallows that, but you can pick your spots.

For me, the following UFC Vegas 43 bets stand out the most.

  • Michael Chiesa to Win (+138)
  • Miesha Tate to Win (+100)
  • Adrian Yanez by KO/TKO (-105)

You can roll with my UFC Vegas 43 DFS picks and/or target my favorite bets. I’ve been 50% or better with my bets lately, while the DFS side of things is just really hard to nail completely.

I’d certainly suggest using my top MMA DFS lineup, but also making numerous pivots while entering a ton of lineups. For the betting side of things, be sure to check out this betting guide for UFC Vegas 43 before placing any bets.

Betting Tips for UFC Vegas 43 With Odds and Top Picks

My predictions and picks for UFC Vegas 43 are set in stone. This weekend’s fights go down on Saturday, November 20 at the UFC Apex. The card is headlined by a women’s bantamweight scrap between Ketlen Vieira and Miesha Tate. Although not the most...

Read More
Noah Davis

Noah Davis is one of the more diverse writers at Like many of his colleagues, he's a huge fan of both football and basketball. But he also writes about box office records, TV show prop bets, DFS, and all kinds of other subjects.

When it comes to the NFL, Noah's favorite team is the Cleveland Browns. He enjoys cheering them on with his wife and daughter.

More Posts by Noah Contact Noah



Back to top