Tuesday’s MLB Predictions and Betting Tips – April 27, 2021

| April 27, 2021 3:03 am PDT

Tuesday’s slate is a full one – all 30 teams are in action, and a bunch of big-time pitchers are set to take the mound. Starting with the first pitch in Cleveland at 6:10 PM ET, the 15 games are packed into a relatively tight window.

That equals a fistful of betting opportunities once the sun goes down.

On that note, let’s explore MLB picks for April 27th.

MLB Game Winner Predictions for April 27th  

  • Indians to beat the Twins
  • Royals to beat the Pirates
  • Orioles to beat the Yankees
  • Nationals to beat the Blue Jays
  • Red Sox to beat the Mets
  • Rays to beat the Athletics
  • Braves to beat the Cubs
  • Brewers to beat the Marlins
  • Cardinals to beat the Phillies
  • Rangers to beat the Angels
  • White Sox to beat the Tigers
  • Astros to beat the Mariners
  • Padres to beat the Diamondbacks
  • Rockies to beat the Giants
  • Dodgers to beat the Reds

A couple of lop-sided price tags are pulling me away from what would otherwise be my top MLB predictions. Walker Buehler is a -235 favorite at home against the Reds; we have to lay -230 if we want to back Lucas Giolito at home versus the Tigers.

It’s easy to say we like the Dodgers and the White Sox in these respective spots. However, it’s hard to consistently stay ahead when betting baseball online if you’re only targeting the massive favorites.

With that in mind, here are two MLB upset picks for Tuesday.

Top MLB Upset Picks for April 27th

  • Orioles +152 (over the Yankees)
  • Red Sox +131 (over the Mets)

The Yankees have been installed as substantial favorites on Tuesday due to their popularity and the public’s perceived conclusions. It has nothing to do with the teams’ performances in 2021 – New York is among the worst hitting teams in all of baseball.

Yankees and Orioles – Comparing Productivity at the Plate
Games Played Runs BA Hits Extra-Base Hits Stolen Bases
Yankees 21 75 .206 141 49 4
Orioles 21 82 .227 159 58 8

*Statistics through Sunday’s Games

Four starts into his career with the Bronx Bombers, and Corey Kluber is yet to complete five innings in a game. Sporting a 5.40 ERA and a paltry 14/11 K/BB ratio, why lay -165 to trust Kluber on the road?

Instead, invest in the home team at +152. Bruce Zimmerman is an up–and coming southpaw who’s looked much better than Kluber thus far.

Staying on theme with fading teams from the Empire State, it seems natural to ride with guys from Beantown.

Coming off a terrible outing on April 21st against Toronto, Garrett Richards is looking to redeem himself Tuesday night in the Big Apple. The good news is Richards is aided by the best hitting team in the big leagues, and he’s facing an erratic young pitcher who’s armed with a 6.75 ERA.

As dominant as Boston’s hitters have been, it’s a bit perplexing that a team that’s 6-1 on the road is a +131 underdog. That’s simply too much free juice to pass on.

Best MLB Bets for Tuesday, April 27th  

  • Indians over the Twins (-105)
  • Nationals over the Blue Jays (-140)
  • Braves (-1.5) over the Cubs (+120)

I had to do a double-take when I spotted Cleveland and Minnesota evenly-priced in today’s matchup at Progressive Field. Seeing that I could indeed back the Tribe to win this game outright, laying just -105, I quickly penciled this in as one of my best MLB picks for Tuesday.

Not only is Minnesota trailing Cleveland in the AL West standings, but Terry Francona is sending out a pitcher who’s been fantastic through the first month of the season. On the flip side, Rocco Baldelli is leaning on a right-hander who’s been, how do I put this politely, awful.

Tuesday’s Pitching Matchup in Cleveland
Starts Innings Hits Allowed Earned Runs Strikeouts
Aaron Civale (CLE) 4 26.0 14 7 22
Kenta Maeda (MIN) 4 17.2 28 12 17

Moving into another one of my top MLB predictions for April 27th; Toronto is handing the ball to Trent Thornton for a spot start. The 6’0” 195-pound righty has appeared in six games for the Blue Jays this season but hasn’t topped 34 pitches in any of his showings. He’s thrown under 30 pitches in each of his last five appearances – look for this to be a “bullpen game” for Charlie Montoyo.

On the opposite end of the spectrum, Max Scherzer takes the ball for Washington, aiming for another gem. Scherzer is looking like his old self over his last two starts having compiled 19 Ks across 13 scoreless innings. Considering I’d lay -170 in the spot without even blinking, the -140 price tag at BetOnline most definitely caught my attention.

Rather than cough up -165 on Atlanta, latching onto the run line (-1.5) allows us to capture the Braves at +120. Ian Anderson shut down the Yankees lineup last time out and garnered a bunch of confidence along the way.

Whether it was fooling Aaron Hicks with a nasty off-speed pitch or setting the record for the most strikeouts by any Braves pitcher through his first 10 starts, look for Anderson to “take no prisoners” in this evening’s pursuit.

Did I mention that Brian Snitker’s group is an impressive 5-1 as an underdog on the run line? Or that the Cubbies are just 4-8 ATS as a favorite on the run line?

It all adds up to Atlanta (-1.5) being one of the top MLB picks today.

Michael Wynn
Michael Wynn

As a former Division I collegiate golfer, Michael Wynn loves writing about golf. He's also an expert in most of America's most popular sports, writing extensively for GamblingSites.com on football, basketball, and baseball.

Michael's a Las Vegas native and has been with the company since 2017.

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