Rams vs. 49ers Player Props for Monday Night Football – Week 10, 2021

| November 14, 2021 9:05 pm PDT

The Los Angeles Rams hope to deal the finishing blow to the San Francisco 49ers on Monday Night Football in week 10.

It’s potentially the perfect nightcap for the week, as the trendy Super Bowl contenders could unleash new weapon Odell Beckham Jr. The 49ers, meanwhile, could be inching closet to permanently setting up shop in the Trey Lance era.

The game itself doesn’t promise to stay close. The Rams are somehow just 3.5-point favorites, of course, so perhaps you could use a little help betting on this one.

For the game itself, check out our week 10 Rams vs. 49ers betting pick. I’m tackling the best Monday Night Football player props here, so join me for my favorites below.

Matthew Stafford Over 2.5 Passing Touchdowns (+160)

I like to keep things simple when handing out my favorite Monday Night Football player props. A downside to that is I don’t chase plus money for the sake of doing it, so you have to work for your wins.

This is a nice exception I don’t mind making, as Stafford and the Rams are sure to bounce-back after getting stifled by the Titans last week.

Getting shiny new toy Odell Beckham Jr. in town can’t hurt, either.

Stafford has been a bit banged up lately, but he’s topped this 2.5 passing touchdown threshold five times in 2021.

The best sites for betting on the NFL also have this game set up with a healthy 50 game total, so some scoring is going to be had.

San Francisco isn’t the easiest matchup, but after being held in check last week, I love the Rams to pop off in an emphatic divisional win.

Jimmy Garoppolo Over 0.5 Interceptions (-118)

Jimmy G’s tenure with the 49ers is nearing an end, but he has one last chance to lead the Niners to glory at home against the Rams on Monday Night Football.

I don’t see it ending well, though.

L.A. has a stacked offense, but they’re just as loaded defensively these days. They can get after you, and they can make things tough in coverage, as well.

Garoppolo isn’t necessarily an interception machine, but all five of his picks have come over his last five games. He’s tossed at least one interception in four of his last five contests, and this just feels like a brutal matchup for him.

At some point Garoppolo will feel the pressure to force the issue, and at -118, I don’t mind betting on a pick going to the Rams.

Odell Beckham Jr. to Score a Touchdown (+175)

I didn’t set out to attack plus money Monday Night Football player prop bets, but here we are.

The reality is the Rams didn’t acquire Odell Beckham Jr. for no reason. He’s going to be active on Monday, too, and L.A. is going to work to get him the ball.

I would have much greater hesitation when it comes to betting on Odell Beckham Jr.’s catches or yardage totals.

But if I love Stafford to get back on track and score three times through the air, you better believe I’ll double down and get Beckham’s score at +175.

My Top Monday Night Football Player Prop for Week 10

Pick
  • Brandon Aiyuk Over 49.5 Receiving Yards
    -115

There are several other Monday Night Football player props I like for week 10. You can bet on Deebo Samuel, Elijah Mitchell, and of course Cooper Kupp.

Rather than chase the star power, though, I just want to target the best bets. Of all the options, my favorite bet is Aiyuk getting to 50+ receiving yards.

Deebo Samuel has the better role, but my guess is he’ll see more of Jalen Ramsey in coverage.

If that ends up being true, Aiyuk’s week 9 blow-up could continue, and the spread and game total arguably contribute to the logic of Aiyuk being needed.

Think the Niners can flip the script? Then go after Elijah Mitchell’s rushing yardage total (Over 63.5, -114).

These are my favorite Monday Night Football player props, however. If you want to bet on these or other NFL player prop bets, brush up on the best ways to do so below.

Noah Davis

Noah Davis is one of the more diverse writers at GamblingSites.com. Like many of his colleagues, he's a huge fan of both football and basketball. But he also writes about box office records, TV show prop bets, DFS, and all kinds of other subjects.

When it comes to the NFL, Noah's favorite team is the Cleveland Browns. He enjoys cheering them on with his wife and daughter.

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