Picks and Predictions for La Liga Games – Round 33 (April 19-21, 2022)

Round 33 sees all 20 La Liga teams in action between Tuesday, April 19, and Thursday, April 21. As we head into the business end of the season, both the top-four race and relegation battle are far from finished.
Real Madrid is 15 points clear atop the La Liga standings. But with second-place Barcelona and sixth-place Real Sociedad separated by just five points, the three remaining Champions League spots are still up for grabs.
At the opposite end of the table, there are ten points between the bottom eight teams. Alaves, Levante, and Mallorca occupy the bottom three, but Granada, Cadiz, Getafe, Rayo Vallecano, and Elche are not safe.
Join me as I go over my La Liga predictions for Round 33. I have also scoured the best La Liga betting sites to find the top picks for Round 33. If that sounds good to you, then let’s get this show on the road!
La Liga Odds and Fixtures for Round 33
- Mallorca (2.10) vs. Alaves (3.75)
- Real Betis (1.57) vs. Elche (6.00)
- Villarreal (1.45) vs. Valencia (6.50)
- Atletico Madrid (1.30) vs. Granada (11.00)
- Celta Vigo (2.15) vs. Getafe (3.75)
- Osasuna (5.00) vs. Real Madrid (1.70)
- Espanyol (2.40) vs. Rayo Vallecano (3.10)
- Levante (3.60) vs. Sevilla (2.05)
- Cadiz (3.40) vs. Athletic Bilbao (2.25)
- Real Sociedad (3.30) vs. Barcelona (2.15)
According to Betway, Real Madrid, Sevilla, Athletic Bilbao, and Barcelona are all favored to win away from home in Round 33. That means there are plenty of tasty La Liga odds to take advantage of this week.
As you can see, Real Betis, Villarreal, and Atletico Madrid are all heavy home favorites. Mallorca, Celta Vigo, and Espanyol are also favored to win on home soil, although their odds are much higher.
It’s time to dive into my Round 33 La Liga predictions.
Atletico Madrid to Beat Granada
Atletico Madrid held onto fourth place with a 2-1 victory over Espanyol at the weekend. Yannick Carrasco scored both of Atleti’s goals, including the winning penalty in the 100th minute!
Not only have Diego Simeone’s men won seven of their last eight La Liga games, but they have also won ten of their previous 14. As a result, they find themselves three points inside the Champions League places.
Only two sides have won fewer games than Granada this season, while only the bottom three teams have registered more losses. For that reason, in-form Atletico should dispatch struggling Granada with ease.
Real Madrid to Beat Osasuna
On Sunday, Los Blancos found themselves 2-0 inside 25 minutes against Sevilla. Remarkably, they ended up claiming all three points thanks to second-half goals from Rodrygo, Nacho, and Karim Benzema.
Benzema has racked up a whopping 36 goal involvements in La Liga this season, bagging 25 goals and 11 assists. With Vinicius Junior also in red-hot form, it is only a matter of time until Real Madrid secures the La Liga title.
- Karim Benzema, Real Madrid (25 goals/11 assists) – 36
- Vinicius Junior, Real Madrid (14 goals/10 assists) – 24
- Raul de Tomas, Espanyol (15 goals/3 assists) – 18
Granted, Osasuna is not a bad team. Los Rojillos have won three of their past four matches and are on course to register a top-half finish. But they will almost certainly struggle to deal with rampant Real Madrid.
Having won seven of their previous eight league outings, Carlo Ancelotti’s boys should see off Osasuna without any problems.
Espanyol to Beat Rayo Vallecano
There is no hiding the fact that Rayo Vallecano is in a real mess. Following last weekend’s 1-0 defeat to Alaves, Rayo heads into Round 33 on a 13-game winless run in La Liga.
Meanwhile, Espanyol sits five points clear of Rayo after notching three shutout wins across the past six rounds. Given the contrasting form of these two sides, I’m confident that Espanyol will claim all three points on Thursday.
More La Liga Predictions for Round 33
- Mallorca and Alaves to Draw
- Real Betis to Beat Elche
- Villarreal to Beat Valencia
- Celta Vigo to Beat Getafe
- Sevilla to Beat Levante
- Cadiz and Athletic Bilbao to Draw
- Real Sociedad and Barcelona to Draw
I expect the bottom-three battle between Mallorca and Alaves to end in a draw. I can also see both Cadiz vs. Athletic Bilbao and Real Sociedad vs. Barcelona ending in a draw, given the importance of those games.
I’m backing Real Betis, Villarreal, and Celta Vigo to win on home soil in Round 33. Elsewhere, I’m confident that third-place Sevilla will dispatch nineteenth-place Levante in Valencia.
Best La Liga Bets for Round 33
- Villarreal vs. Valencia – Both Teams to Score (1.90)
- Atletico Madrid vs. Granada – Atletico Madrid to Win and Over 2.5 Goals (1.95)
- Levante vs. Sevilla – Sevilla to Win (2.05)
Villarreal is priced at 1.45 to beat Valencia. In my eyes, though, the BTTS wager offers far better value. Why? Because both teams have scored in 22 of Valencia’s 32 La Liga games this season.
You can get odds of 1.30 for Atletico to beat Granada, so I recommend throwing the over 2.5 goals market into the mix. Let’s not forget that 66% of Atleti’s league games have dished up over 2.5 goals this term.
Finally, I’m backing Sevilla to beat Levante. Since the teams are separated by a whopping 35 points in the standings, odds of 2.05 for the Sevilla win feel too good to miss.
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