MLB Predictions and Best Bets – September 12, 2020

| September 11, 2020 12:01 pm PDT

Gear up for another fun MLB betting slate with our daily baseball betting preview, which focuses on game-winner predictions and top betting picks.

Despite a full slate of 16 games, I like to condense things and focus on the best situations to place bets.

Here’s a look at the games I like to target for Saturday’s MLB betting action.

  • Pirates vs. Royals
  • Cubs vs. Brewers
  • Astros vs. Dodgers
  • Indians vs. Twins
  • Angels vs. Rockies
  • Mariners vs. Diamondbacks
  • Reds vs. Cardinals

That gives us seven fun games to work with. There are nine others you can certainly entertain betting on, but these are the games where I like the straight-up picks the most, and/or see another bet we can exploit.

For my MLB predictions and top betting picks for Saturday, read on.

Pirates vs. Royals Predictions

  • Royals to beat Pirates
  • Predicted total: 8-8.5

A day after getting Kris Bubic, Pittsburgh has a tougher matchup against KC youngster Carlos Hernandez. The young righty has some nice tools, including a solid fastball, and a filthy changeup.

Pittsburgh is really only a threat in advantageous spots, and this isn’t one. On the other side, Kansas City has a good shot at beating up on the hittable Trevor Williams.

Cubs vs. Brewers Predictions

  • Cubs to beat Brewers
  • Predicted total: 8-8.5

Milwaukee had a solid matchup yesterday, but on Saturday they face a controlled pitcher in Kyle Hendricks. I doubt Milwaukee’s inconsistent bats get to him enough, while Brett Anderson is far from an imposing force on the other side.

Astros vs. Dodgers Predictions

  • Dodgers to beat Astros
  • Predicted total: 8.5-9

This is a fun one, as the Dodgers look for some revenge against the team they lost the World Series two years ago. Houston is struggling, while L.A. has excelled all year long.

The pitching matchup is a wash, so the edge understandably goes to the home (and better) squad.

Indians vs. Twins Predictions

  • Indians to beat Twins
  • Predicted total: 8.5-9

This game offers a solid pitching matchup, as southpaw Rich Hill will try to contain the Indians, and Zach Plesac will hope to silence the mighty Twins.

Plesac is a bit more reliable this year, but both of these lineups could still tee off in this park. I like Cleveland to win, but the Over is the preferred bet in this one.

Angels vs. Rockies Predictions

  • Angels to beat Rockies
  • Predicted total: 11-11.5

The Halos continue a fun series at Coors Field, where they get a massive park upgrade. Colorado is at their best at home, but the pitching isn’t great in this one, and the Angels will benefit immensely from this shift.

Los Angeles doesn’t strike out much, and they may have enough power to get to Kyle Freeland early. As always, the Over is one of the better MLB bets to hammer.

Mariners vs. Diamondbacks Predictions

  • Diamondbacks to beat Mariners
  • Predicted total: 8-8.5

This should be a solid spot for a little value, and it also may be a nice opportunity for the D’Backs to get a win. Arizona is at home against the lowly Mariners, and even their watered-down lineup could find some success here.

Neither of these teams are particularly fun to trust, but Zac Gallen (2.29 ERA) has been awesome in 2020 and should shred here.

Reds vs. Cardinals Predictions

  • Cardinals to beat Reds
  • Predicted total: 8-8.5

Lastly, we come to a nice matchup at home for the Cardinals. They’re usually a little more fun against southpaws due to their right-handed power, but they have plenty of lefties to throw at Anthony DeSclafani (7.20 ERA).

The Cincy righty has a wide split and struggles mightily with lefties, and I suspect that continues on the road against the Cardinals.

Best MLB Bets for Saturday, September 12th

MLB odds for Saturday’s baseball betting slate are not out just yet. When they are, I’ll update this section with my top MLB picks, along with a brief analysis.

Just keep in mind that prices can change, while probable pitchers and starting lineups can also change, and/or impact odds.

Looking to bet on baseball today? Whether you use my MLB picks or not, just make sure you’re using the best wagers and odds available.

If you’re unsure where to find them, just take a look at the most reputable baseball sportsbooks before finalizing any bets.

Noah Davis

Noah Davis is one of the more diverse writers at Like many of his colleagues, he's a huge fan of both football and basketball. But he also writes about box office records, TV show prop bets, DFS, and all kinds of other subjects.

When it comes to the NFL, Noah's favorite team is the Cleveland Browns. He enjoys cheering them on with his wife and daughter.

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