Los Angeles Rams vs. Buffalo Bills Betting Preview – NFL, September 27, 2020

| September 23, 2020 5:14 am PDT

After opening up with a couple of AFC East cupcakes, the Bills are right where we expected them to be – sitting pretty at 2-0. On the other hand, most didn’t anticipate the Rams getting the party started with a victory over the Cowboys. I certainly didn’t suspect LA to lay a resounding beatdown on the Eagles.

With Buffalo and Los Angeles both currently undefeated, something’s got to give on Sunday afternoon in Orchard Park.

This Rams vs. Bills prediction post sets the stage.

Rams vs. Bills Odds

Rams (+2.5)-115
Bills (-2.5)-105
Rams to Win+115
Bills to Win-135
Over 47.5-110
Under 47.5-110

After Vegas opened this line with the Bills laying a field goal, the top NFL betting sites quickly slid the number down to 2.5. A few bookies even have the Rams getting just 2 points, although there’s some “other” line movement to be aware of.

The original 44.5-point total is nowhere to be found. The total has been pushed all the way up to 47.5 nearly everywhere you look.

Rams vs. Bills Matchup

It’s probably too late to go snag Darrell Henderson in your fantasy league but do so if you can. The Rams second-year RB could be in line for a huge chunk of snaps come Sunday.

However, regardless of which of Sean McVay’s running backs shoulder the load in Buffalo, it’s unlikely that any of them will sustain much success. Buffalo has surrendered just 75.5 rushing yards per game (3rd in the NFL) through the first two weeks.

Expect to see lots of quick-hitting plays featuring Cooper Kupp and Robert Woods. Sean McDermott is probably blue in the face from watching Tyler Higbee score three touchdowns in Philly, but that won’t stop Jared Goff from seeking out his tight end early and often.

The Los Angeles offense should ultimately find a few creases in the Bills defense, but falling into a rhythm and steadily moving the chains is going to be a tall order.

When Josh Allen and his crew have the ball, they won’t have the luxury of competing against another depleted group. After making the Jets and Dolphins secondaries look like a couple of JV squads, Allen should start coming back down to Earth against a bunch led by Jalen Ramsey and John Johnson.

Oh yeah, and that Aaron Donald guy is pretty good at applying pressure.

Rams vs. Bills Pick

The Buffalo defense is a nasty unit, especially at home.

Aaron Donald anchors a determined D-line in LA that made mincemeat out of Carson Wentz last weekend. Los Angeles also held an explosive Cowboys team to 17 points in the opener.

As solid as Josh Allen and Jared Goff have each looked in the early going, look for both of these offenses to hit a bit of a wall come Sunday.

My Rams vs. Bills prediction is that we see a hard-fought game that likely comes down to the wire. Buffalo should be able to escape win, but attacking the under is my favorite bet of the game.

Pick
  • Under 47.5
    -110
Michael Wynn

As a former Division I collegiate golfer, Michael Wynn loves writing about golf. He's also an expert in most of America's most popular sports, writing extensively for GamblingSites.com on football, basketball, and baseball.

Michael's a Las Vegas native and has been with the company since 2017.

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