Best Bets for NFL Parlays in Week 16, 2020

| December 22, 2020 9:06 am PDT

Anytime you piece together parlay picks for NFL betting, you want winning bets. Ideally, you get a string of bets that convert and also offer nice upside.

I try to aim high each week, which tends to include a risky underdog play to really take things up a notch. The Eagles almost looked like a brilliant addition to my NFL parlay last week but ultimately failed.

The total in the Packers vs. Panthers game was also disappointing, but I did correctly predict the Bucs and Seahawks getting wins. Two out of four NFL picks, in general, isn’t bad, but when you’re betting on NFL parlays, it is worthless.

The goal remains the same as I issue my favorite parlay picks for NFL week 16 betting; to get every bet right and to return bettors elite value. Let’s see what my favorite NFL parlay is this week.

Vikings vs. Saints Over 52 (-105)

The first game of week 16 may be one of the most explosive. Drew Brees played horribly last week, yet he still generated 29 points in a game that totaled 61 points.

New Orleans needs to put points on the board to get back on track, especially if they have plans on catching the Packers to nab the #1 seed in the NFC.

You can try to bet on the Saints just winning this game, but the Vikings are pesky and have a lot of offensive talent. That could make betting on the moneyline or spread a bit problematic.

What I’m not worried about is the scoring here, though. Minnesota’s defense has not been good all year, and though the Saints have a strong roster on that side of the ball, they’ve bent a lot more than expected lately.

This game projects as a shootout. Whether the Vikings help push the pace early or put up points in comeback mode, I think the Over is a great bet.

Miami Dolphins (-3) -105

Miami is among my best bets for week 16, as they can smell the playoffs and will be looking to send the Raiders packing.

Las Vegas is collapsing at the wrong time, and they’re basically out of it at this point. Not just that, but they’ll probably have to hope backup quarterback Marcus Mariota has another spirited effort in him.

One thing is for sure, it’ll be must-see TV.

Mariota looked great in relief of an injured Derek Carr last week, but will he be as effective when a good Miami defense has an entire week to prepare for him?

My guess is no.

Even if I’m wrong, Miami’s offense should still get the job done here, as the Raiders continue to be one of the worst defensive units in the league.

Miami as a straight-up pick is a bit safer, but they should be able to cover this spread and squeeze a bit more value out for this week 16 NFL parlay.

Arizona Cardinals to Win (-210)

The Cardinals are probably fine to cover a four-point spread, but I’m a little worried that a well-coached 49ers team will refuse to quit.

That shouldn’t prevent Arizona from a much-needed win, though. While it could be closer than some may think, the Cardinals have too much to play for to lie down at home.

They beat a much stronger 49ers team to start the season back in week one, and Arizona has looked like a team capable of pushing for the playoffs all year.

This may be where the Cardinals punch their ticket, as a loss would put them at serious risk of sliding out of contention. The odds aren’t amazing as a one-off wager, but as part of my parlay picks for week 16, this will do just fine.

Tennessee Titans to Win (+160)

I feel very confident that the Vikings vs. Saints game will be en fuego and that both Arizona and Miami will get wins, maybe even relatively comfortably.

If you want to play it safe, you can dial things back a bit and stick to those three picks for your week 16 NFL parlay. In doing so, you’d get back $380.35 for every $100 risked at Bovada.

That’s a very solid payout for three wagers that individually do not give out plus money.

I’d rather just take things up a notch, though, especially when I see a great opportunity for the Titans to get a huge road win against the Packers.

Green Bay is a very good team, and they’ve proven that all year with a stout 11-3 record. They also tend to be pretty strong in primetime spots.

However, the Packers were very sluggish for half of their close win over the Panthers last week, and without a full stadium at Lambeau Field this year, they’ve had quite a few disappointing home efforts.

Some can look back and recall a “meh” performance in a win over the Falcons, a mini-collapse against the Eagles, a loss to the Vikings, and a near-loss to the Jaguars.

Green Bay also has no real “trademark” win on their schedule. They beat the Saints back in week three, but that feels like forever ago.

This is also a bad matchup for the Packers. Derrick Henry is a battering ram that they can’t possibly hope to stop. Green Bay’s run defense, in general, is not very good, and their tackling is even worse.

That’s bad news against Henry.

Even if the Packers do somehow stop Henry, they need to worry about Ryan Tannehill and a lethal Titans passing game. This all is worrisome, and then a Packers offense that stalled out last week needs to make sure they don’t do so again.

Tennessee is a very good team, and they have a division crown on the line here. My guess is they put up a ton of points here and squeak one out in a shootout.

Top Week 16 NFL Parlay Bet

  • Vikings vs. Saints Over 52 (-105)
  • Miami Dolphins (-3) -105
  • Arizona Cardinals to Win (-210)
  • Tennessee Titans to Win (+160)

As usual, you can attack each of these bets individually, cut the parlay down to the picks you really feel good about, or even alter some of the picks.

Maybe you want Miami SU, Arizona to cover, or Tennessee against the spread. The exact combination is up to you, but I love these four bets, and a $100 wager at Bovada would bring back a cool $1,148.90.

There are always ways to play it safe and bring back plenty of profit, but I prefer to aim high. Hopefully, my week 16 NFL parlay does that and also converts for my readers.

For a little more NFL betting advice for this week hit the links below.

Noah Davis

Noah Davis is one of the more diverse writers at Like many of his colleagues, he's a huge fan of both football and basketball. But he also writes about box office records, TV show prop bets, DFS, and all kinds of other subjects.

When it comes to the NFL, Noah's favorite team is the Cleveland Browns. He enjoys cheering them on with his wife and daughter.

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