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Top Waiver Wire Pickups for Week 2 in Fantasy Football Leagues (2021)

| September 14, 2021 3:47 am PDT

Week 1 of the 2021 fantasy football season was incredible in a lot of different ways. We had huge games from some of our favorite fantasy players and some huge duds.

With Week 2 now on the slate, it’s time to look at which players you should be spending your waiver wire picks on.

There were also some unfortunate injuries that could open opportunities for other players.

Let’s look at the best fantasy football waiver wire pickups for Week 2 of the fantasy season.

Eli Mitchell, RB, San Francisco 49ers (7% Owned)

Raheem Mostert went down with an injury in the first quarter of Week 1, and Trey Sermon was listed as inactive (coach’s decision), which opened the door for Eli Mitchell.

Mitchell being listed as active and Sermon being listed as inactive is a big indication that the 49ers trust Mitchell more than Sermon, even though Sermon was drafted three rounds earlier than him.

Mitchell was great in Week 1 against the Lions. His big highlight play came early in the second quarter, when he busted a 38-yard touchdown to give the 49ers a 13-7 lead.

He finished the game with 19 carries for 104 yards (5.5 yards per carry) and a touchdown.

Mitchell looks to be the starter moving forward with the severity of Raheem Mostert’s knee injury unknown. Mostert is known for being injury prone, so even if he isn’t out long, Mitchell is set up for a solid rookie season.

Look for Sermon to be listed as active in the next one and try to make a better impression moving forward.

Don’t think the only reason why Mitchell had a big game is because of the Lions being terrible, because the 49ers rush attack is lethal no matter their opponent. Mitchell needs to be added to your fantasy lineups.

Mark Ingram II, RB, Houston Texans (19% Owned)

Volume is everything in fantasy, and Mark Ingram II got a bunch of it in Week 1. The Texans have a three headed monster in their backfield, but Ingram is the clear lead back.

He ran the ball a whopping 26 times against the Jaguars, while Lindsay and Johnson finished with 11 carries between the two of them (eight for Lindsay, three for Johnson).

Ingram did not have a super-efficient game, with just 3.3 yards per carry, but he ran for 85 yards and a touchdown.

If Ingram gets that kind of work in every game, he is going to be a fantasy steal.

He might not get a ton of touchdowns and the other backs may steal some touches from time to time, but he could have a high floor, which is great for fantasy and deeper leagues.

Tim Patrick, WR, Denver Broncos (1% Owned)

Another player who will have more opportunities due to a teammate’s injury is Tim Patrick.

Broncos promising young wide receiver Jerry Jeudy suffered an ankle injury, which will knock him out for at least a couple of weeks.

Jeudy was going to be a big part of the offense, so his absence leaves a lot of targets up for grabs.

K.J. Hamler is also an interesting option here and dropped a deep touchdown in Week 1, but Patrick should be the pickup. Patrick should slide into Jeudy’s role while Hamler plays more of a slot role.

Patrick finished with four catches on four targets for 39 yards and a touchdown against the Giants and gets an even easier matchup with the Texans in Week 2. Jeudy had six catches on seven targets, so Patrick should be able to get six-eight targets easily with Jeudy out.

Grab Patrick for now, as Jeudy could miss up to half the season.

James White, RB, New England Patriots (33% Owned)

James White did not have a lot of success with Cam Newton at quarterback, but it looks like Mac Jones has found a solid connection with him.

In their first start together, White caught six passes on seven targets for 49 yards. He also added 12 yards rushing on four attempts.

His 61 total yards might not seem like a lot to be excited about, but if you are in a PPR league, he should have scored 13 fantasy points.

That is very solid production and can make for a solid flex play moving forward. If he sprinkles in some touchdowns with that amount of work in the receiving game, he can be a very solid fantasy option.

He does bring some risk with him, as the Patriots backfield is very hard to predict, but White has been very solid in fantasy when Brady was in New England and now looks to be back with Mac Jones.

Jared Cook, TE, Los Angeles Chargers (26% Owned)

For some reason, Jared Cook flew under everyone’s radar in fantasy drafts.

For those teams who did not land a top four tight end, I would heavily consider grabbing Jared Cook.

Despite a tough matchup with a good Washington defense, here’s what Cook managed in week one.

  • 8 targets
  • 5 receptions
  • 56 receiving yards

He could be in for some very solid production with most of the focus going to Keenan Allen, Austin Ekeler, Mike Williams, and their speedy slot receivers.

Cook knows how to score as well, with at least six touchdowns in the past three seasons.

His targets and production in Week 1 indicate him being a nice option from the tight end position in the Los Angeles Chargers’ offense. With very few tight ends outside the top five-six, Cook can be a great pickup for this year.

Fantasy Football Waiver Wire Advice for Week 2

Waiver Wire adds are potential league winners in fantasy football. They fill in for players who miss time and make a name for themselves.

They could be considered “sleepers” because of how difficult it is to predict their opportunities before we see gameplay.

It is also impossible to predict injuries, which is a huge source of opportunity for waiver wire guys.

If you lost a player due to injury like Jerry Jeudy or Raheem Mostert, consider my week two fantasy football waiver wire pickups.

These players all come at a relatively cheap price on the waiver wire, but make sure you know how your waiver settings work.

If you are in a super deep league, you might want to consider spending that waiver wire position on one of these players for Week 2 and moving forward.  

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Anthony Haage
Anthony Haage

Anthony is a sports writer for GamblingSites.com covering the NFL, NBA, MLB, NHL, and more. He also covers other various topics such as entertainment, general sports betting tips, and more.

His favorite teams are the Chicago Bears, Bulls, Cubs, and Blackhawks. He also will be a temporary fan of any team if it means winning him bets.

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