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Opening NFL Odds and Betting Lines for Week 6 (2020)

| October 12, 2020 9:40 am PDT
NFL Week 6 Odds

The 2020 NFL season has been marred by a litany of massive injuries, as well as the negative impact of a global pandemic.

We were reminded of both in week five, as Dak Prescott was another casualty of this weird season, and two games were pushed back due to COVID-19.

As crazy as things have been and could still get from here, this league is still worth betting on. If you play your cards right – and get an early look at NFL odds – you can potentially nail some bets and profit from the madness.

In an effort to help you, here’s a look at the NFL week 6 odds for each game.

Chicago Bears vs. Carolina Panthers

  • Bears (+3) -120
  • Panthers (-3) +100
  • Bears to Win (+125)
  • Panthers to Win (-145)
  • Over 44 (-108)
  • Under 44 (-112)

The Bears pulled out a win over the Buccaneers last week, so they must be legit, right? Carolina has also ripped off three straight wins, so suddenly we need to take them seriously, too.

Good luck figuring this one out, but it’s at least understandable that the Panthers are the light favorites. They’re at home, they’ve won three straight, and they’ve looked better.

You’re getting a solid price no matter which way you lean here, while this game total feels a bit low.

Detroit Lions vs. Jacksonville Jaguars

  • Lions (-3.5) -112
  • Jaguars (+3.5) -108
  • Lions to Win (-190)
  • Jaguars to Win (+165)
  • Over 54.5 (-111)
  • Under 54.5 (-109)

The top NFL betting sites are making you take a stand when it comes to the Lions vs. Jaguars in week six. Detroit goes on the road as nearly four-point favorites, which is a tad alarming since they have won four games in the last year.

Jacksonville could offer nice betting value as the home dog, and recent history suggests they should at least be able to keep it close. The Over is enticing when you look at the lack of defense, but Jacksonville and Detroit are both bottom-12 in plays per game.

Atlanta Falcons vs. Minnesota Vikings

  • Falcons (+3.5) -108
  • Vikings (-3.5) -112
  • Over 56.5 (-110)
  • Under 56.5 (-110)

Atlanta finally did it; they fired head coach Dan Quinn.

This was a move the franchise probably should have done in mid-season last year, but at least we’re finally here. Is it a magical move that will vault the Falcons back to relevancy? I doubt it.

Bettors can still consider Atlanta with the 3.5 points, of course, while this game does project as a potential shootout when you look at the offenses and Atlanta’s terrible defense.

That said, the Vikings have looked a lot better defensively the past two weeks, and the Dirty Birds have just 32 total offensive points in their last two games.

Houston Texans vs. Tennessee Titans

  • Texans (+2) -105
  • Titans (-2) -115

There isn’t a whole lot of betting data to work with for this Texans vs. Titans game, seeing as Tennessee had their week five game pushed to Tuesday thanks to COVID-19.

I’m writing this on Monday so bettors can get a look at early week six NFL odds, so we don’t even know if they beat the Bills or not.

Either way, Tennessee is the better team, so this spread feels a bit too tight, and we should all agree the Titans should be favored on their home field.

Washington Football Team vs. New York Giants

  • Washington (+3) -115
  • Giants (-3) -105
  • Washington to Win (+135)
  • Giants to Win (-155)
  • Over 43 (-110)
  • Under 43 (-110)

The Dwayne Haskins era is over, and so too, is Kyle Allen’s reign. Instead, Washington has gotten Alex Smith back, which by itself makes this season fun.

Smith couldn’t rescue Washington from a tough loss last week, but he is perhaps worth backing in week six against a bad Giants team. I mean, somebody has to win this game, right?

Washington is pretty appealing here, and just due to this total being so low, bettors could entertain throwing caution to the wind and betting on the Over.

Cleveland Browns vs. Pittsburgh Steelers

  • Browns (+4) -115
  • Steelers (-4) -105
  • Browns to Win (+165)
  • Steelers to Win (-190)
  • Over 51 (-110)
  • Under 51 (-110)

The Browns are for real, it appears. Baker Mayfield and co. got it done in a pretty nice win against a solid Colts team, and they’re now 4-1 for the first time since 1994.

Cleveland looks good, but now they are really put to the test against an undefeated Steelers game on the road. Road games aren’t quite what they were pre-COVID, but still.

The Browns could offer sneaky value here, and this game has solid shootout potential.

Baltimore Ravens vs. Philadelphia Eagles

  • Ravens (-7.5) -109
  • Eagles (+7.5) -111
  • Ravens to Win (-350)
  • Eagles to Win (+280)
  • Over 46.5 (-110)
  • Under 46.5 (-110)

Lamar Jackson really wasn’t needed in an easy week five win for Baltimore, but it’s possible the Ravens could be tested on the road against a desperate Philly squad.

The Eagles badly need a win, and this spread does feel awfully thick. Bettors need to weigh the Eagles’ desperation and being at home versus Baltimore simply being a way better team.

Cincinnati Bengals vs. Indianapolis Colts

  • Bengals (+8) -115
  • Colts (-8) -105
  • Bengals (+305)
  • Colts (-375)
  • Over 46.5 (-110)
  • Under 46.5 (-110)

Joe Burrow finally looked like a rookie, as he tossed a careless pick and struggled all day in a lopsided loss to the Ravens. I’m not entirely sure we should demand a whole lot more this week, as he faces a talented Colts defense in Indy.

BetOnline and other NFL sportsbooks are setting the odds that way, at least, with the Bengals entering as 8-point underdogs.

Denver Broncos vs. New England Patriots

  • Broncos (+9) -120
  • Patriots (-9) +100

This game only has a point spread available, as the Broncos and Pats are two more teams who have been impacted by COVID-19 cases. In fact, this could be a game we just have to stay away from, depending on what transpires.

For now, this point spread feels a bit dicey. A Drew Lock return could make the Broncos palatable as an against the spread play, but history suggests Bill Belichick will feast on Denver in this spot.

New York Jets vs. Miami Dolphins

  • Jets (+8) -120
  • Dolphins (-8) +100
  • Over 50 (-110)
  • Under 50 (-110)

Narratives are a heck of a thing in sports. Are the Dolphins suddenly good? It’s hard to think they’re awful, as they just trounced the 49ers and have played pretty well throughout the year.

But are they so good that we can trust them to win by nine at home against New York? Considering the Jets really haven’t been competitive in 2020, it’s something that should be more obvious than it feels.

Is this the week Adam Gase finally gets fired? If so, Miami to cover could be in the cards.

Green Bay Packers vs. Tampa Bay Buccaneers

  • Packers (-2.5) -105
  • Buccaneers (+2.5) -115
  • Packers to Win (-136)
  • Buccaneers to Win (+116)
  • Over 53.5 (-115)
  • Under 53.5 (-105)

Aaron Rodgers is on track to win the 2020 NFL MVP and his Packers are 4-0, so nobody should balk when they enter Florida as mild favorites against the Buccaneers.

The Packers are probably the better team right now, but there is something to be said for traveling over 1,000 miles south and playing a loaded Tampa Bay offense.

Bettors may have trouble picking a side here, but the game total sounds about right. Whether the Over hits or not, a shootout is likely.

Los Angeles Rams vs. San Francisco 49ers

  • Rams (-3.5) -110
  • 49ers (+3.5) -110
  • Rams to Win (-175)
  • 49ers to Win (+155)
  • Over 50.5 (-110)
  • Under 50.5 (-110)

The Rams are very quietly 4-1, and suddenly they enter a key week six showdown with the Niners. They’re respectable favorites here, and after seeing the 49ers meltdown the past two weeks, it’s easy to see why.

This game is going to be tough to peg, largely because we have no clue what the 49ers will (or should) do at quarterback.

San Francisco’s defense even eroded last week (against Miami!), making this one of the dicier games to bet on in week six.

Kansas City Chiefs vs. Buffalo Bills

  • Chiefs (-3) -120
  • Bills (+3) +100

Of course the Chiefs lose the very week I pegged them as the most likely to lose last of all the undefeated teams in 2020. Isn’t that always how it goes?

It seems so, and it was made worse due to them being massive 13-point favorites over the rival Raiders.

They’ll surely be looking to bounce back in a big-time showdown with Buffalo. This game should feature a ton of big plays, but right now all you can bet on is the spread. It’s priced appropriately, and KC at -3 could be a bit of a steal.

Arizona Cardinals vs. Dallas Cowboys

  • Cardinals (-2.5) -116
  • Cowboys (+2.5) -104
  • Cardinals to Win (-145)
  • Cowboys to Win (+125)
  • Over 54.5 (-110)
  • Under 54.5 (-110)

Lastly, we come to a pretty interesting game between the Cardinals and Cowboys. Arizona is back on track after dominating last week, and they could move to 4-2 with a win here.

The top NFL sportsbooks peg them as the slight favorite, but this spread could easily be thicker when you consider Dak Prescott’s season-ending injury.

You could be getting value via the Cardinals early in the week, while the game total also looks appealing. Dallas just gave up 34 points to the Giants, after all.


What’s the point in getting an early look at week six NFL odds and analyzing the early lines?

Value, my friends.

This Cardinals spread and moneyline is a great example of locking in value that will probably decrease as the week goes on, while other games with tight spreads or low totals could be exploited right now.

NFL betting lines can move either way throughout the week, but you’re often going to get the best possible odds on Monday or Tuesday. For games that seem uncertain due to COVID-19 or player injuries, you’re likely going to want to attack even more.

It’s up to you how to bet on these games, but getting a head start on week six is still something you’ll want to do. If you need a little help dissecting each game, feel free to check out our NFL betting picks section, too.

Noah Davis
Noah Davis

Noah Davis is one of the more diverse writers at GamblingSites.com. Like many of his colleagues, he's a huge fan of both football and basketball. But he also writes about box office records, TV show prop bets, DFS, and all kinds of other subjects.

When it comes to the NFL, Noah's favorite team is the Cleveland Browns. He enjoys cheering them on with his wife and daughter.

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