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Picks and Predictions for MLB Games on Tuesday, June 21st, 2022

| June 21, 2022 6:38 am PDT
MLB logo, generic baseball field, odds and predictions

My MLB picks on Tuesday, June 14, didn’t have a great start. It wasn’t looking after the losses by the Philadelphia Phillies and Toronto Blue Jays. Well, it turns out that those were our only losses of the day, as we went 8-2.

It was another perfect day for my best bets. A $10 wager on each best bet this season would have you profiting over $150.

The MLB odds have ten games on the board for Tuesday. Will my MLB predictions have another profitable day? Let’s check it out.

Where to Bet on the MLB Games on Tuesday

It’s important to examine the top MLB betting sites before making your MLB picks today. BetOnline is my go-to site for MLB betting odds because they always have odds available the day before.


Bovada, BetUS, and MyBookie typically post their odds later in the day, but they’ll be available by Tuesday morning. That gives you ample time before making your MLB picks.

I’d recommend creating an account ahead of time, so there aren’t any interruptions with the games fast approaching. No one wants to be in a situation where they miss a profit because of an error with their account.

MLB Odds for Tuesday, June 21st, 2022

  • Dodgers (-184) vs. Reds (+169), O/U 9.5
  • Rockies (+116) vs. Marlins (-126), O/U 8.5
  • Cubs (+119) vs. Pirates (-129), O/U 8.5
  • Tigers (+166) vs. Red Sox (-180), O/U 9.5
  • Phillies (-105) vs. Rangers (-105), O/U 9
  • Cardinals (+108) vs. Brewers (-118), O/U 8.5
  • Blue Jays (-120) vs. White Sox (+110), O/U 8.5
  • Mets (+121) vs. Astros (-131), O/U 9
  • Royals (+154) vs. Angels (-167), O/U 8.5
  • Mariners (-139) vs. Athletics (+129), O/U 7

Before we start the betting trends, I want to point out that the Baltimore Orioles will battle the Washington Nationals. We don’t have odds yet, but that matchup features the best team against the spread against the worst.

There are a pair of matchups on the board with a team top ten against the spread against a bottom ten team. The Los Angeles Dodgers and St. Louis Cardinals are among the league leaders against the spread, while the Cincinnati Reds and Milwaukee Brewers rank near the bottom.

The only matchup with two bottom teams against the spread is the Toronto Blue Jays vs. Chicago White Sox.

Let’s see if the run total affects my free MLB picks.

The Colorado Rockies vs. Miami Marlins matchup opens with 8.5 runs. That’s important because it’s the only matchup with two teams ranking top ten at going over their run total.

On the flip side, the Detroit Tigers and Boston Red Sox are among the league leaders at going under their run total. It’s surprising to see the run total open at 9.5. Will the MLB odds favor a low-scoring game?

We’ll see a significant disparity between the New York Mets and Houston Astros. New York has a 36-28-4 record on the run total, while Houston is 21-44-1.

Top MLB Predictions for Tuesday’s Games

  • Dodgers Over Reds
  • Marlins Over Rockies
  • Pirates Over Cubs
  • Red Sox Over Tigers
  • Rangers Over Phillies
  • Cardinals Over Brewers
  • White Sox Over Blue Jays
  • Mets Over Astros
  • Angels Over Royals
  • Mariners Over Athletics

My MLB betting picks have the Los Angeles Dodgers kicking the day off with a victory. Tony Gonsolin has led the Dodgers rotation, holding a 1.19 ERA in his last five starts. He shouldn’t have an issue with the Cincinnati Reds.

There likely isn’t much excitement surrounding the next two matchups, but I have the Miami Marlins and Pittsburgh Pirates scoring victories.

Since May 13, the Boston Red Sox have the second-best record. The Detroit Tigers’ offense remains one of the worst in the majors. My MLB expert picks are siding with the Red Sox.

The Philadelphia Phillies have been great in June, but I’m taking the Texas Rangers. Philadelphia is the better team, but Texas has Martin Perez on the mound.

  • 4-2
  • 2.10 ERA
  • 1.11 WHIP
  • 18 Walks
  • 65 Strikeouts

The St. Louis Cardinals and Milwaukee Brewers are in a tight battle for the NL Central. Milwaukee’s rough month has me taking St. Louis in this matchup.

My MLB predictions feature value with the Chicago White Sox and New York Mets scoring victories. I’ll talk more about each team later, but how often will you see the Mets as the underdog in 2022?

The latest 2022 AL MVP odds had Mike Trout as a top contender. He only strengthened his claim with an unbelievable performance against the Seattle Mariners.

Speaking of the Mariners, I like their chances to take down the Oakland Athletics. My MLB free picks don’t have much confidence in the Athletics, no matter the opponent.

Best Bets for the MLB Games on 6/21/22

  • White Sox to Win (+119)
  • Mets to Win (+121)
  • Cardinals vs. Brewers Over 8.5 Runs (-110)

We expected the Toronto Blue Jays and Chicago White Sox to compete for the AL Pennant. Toronto has overcome a slow start to be a contender, but Chicago remains under .500. However, I’m backing the White Sox on Tuesday.

My free MLB pick today for this matchup revolves around the starting pitchers. Blue Jays starter Kevin Gausman looked like an early Cy Young contender, but he has a 4.37 ERA in his last seven starts.

White Sox starter Dylan Cease hasn’t allowed a run in 20 straight innings. That should give Chicago the advantage.

The New York Mets open as the underdog against the Houston Astros. They have the second and third-best record in the league, but the pitching matchup makes me wonder why the Mets aren’t the favorite.

Houston starter Jose Urquidy has been disappointing this season. He has a 4.99 ERA and 1.52 WHIP. He had a nice stretch in May, but Urquidy has allowed 20 runs in his last 32.2 innings. I wouldn’t want a struggling pitcher on the mound against the Mets.

Pitching has been a theme with my MLB expert picks. Let’s keep it going with the St. Louis Cardinals vs. Milwaukee Brewers. Jack Flaherty recently made his season debut, but it didn’t go well.

  • 3.0 innings
  • 3 hits
  • 2 runs
  • 2 walks
  • 3 strikeouts

Milwaukee will likely go with a bullpen game after placing projected starter Aaron Ashby on the IL. Their bullpen has been good but not great this season. That could spell trouble against a potent Cardinals offense.

Hopefully, the pitching change doesn’t significantly impact my free MLB picks.

Best Player Props for June 21st, 2022

  • C.J. Cron to Record an RBI (+130)
  • Xander Bogaerts to Record a Hit (-290)
  • Tyler Mahle Over 5.5 Strikeouts (-142)

My MLB picks might not align with yours, so why not examine my favorite player props for Tuesday’s MLB action.

C.J. Cron has been a pleasant surprise for the Colorado Rockies. Cron is on pace to make his first All-Star game after hitting .298 with 17 home runs and 52 RBIs. He’s coming off a fantastic series against the San Diego Padres.

He went 7-13 with three home runs and eight RBIs in the three-game series. San Diego is one of the top teams in the NL, but they had no answer for Cron. He should record another RBI as the Rockies face the Miami Marlins.

Xander Bogaerts has been producing strong numbers throughout the 2022 season, but not many players can match his recent stretch. It’s a big reason my MLB picks today have the Boston Red Sox winning.

Bogaerts went 0-4 on Sunday, marking the second time he failed to record a hit in June. He raised his batting average from .322 to .342 in his 11-game hit streak. There isn’t much value with Bogaert’s recording a hit, but it should be an easy profit.

Cincinnati Reds starter Tyler Mahle doesn’t have the best ERA, but he has been striking out players at will lately. He’s coming off his best performance of the season, a 12-strikeout shutout against the Arizona Diamondbacks.

Over the last five starts, Mahle has the most strikeouts for any starter. He has cleared 5.5 strikeouts in seven of his last eight games. My MLB baseball free picks would consider the alternate line, but a matchup with the Los Angeles Dodgers have me remaining at 5.5.

Please visit our MLB blogs page for more MLB content.

Nicholas Sterling
Nicholas Sterling

Nicholas has been a Sports Writer with GamblingSites.com since May 2021. He has a rich sports background, writing about NASCAR, NFL, NBA, MLB, NHL, Golf, etc. Nick is always ready for a new challenge.

He enjoys rooting on D.C. sports teams, including the Commanders, Wizards, and Capitals.

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