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Early Betting Odds and Lines for NFL Week 10 (2020)

| November 9, 2020 1:49 am PDT
Early Betting Odds and Lines for NFL Week 10 in 2020

If you were ever unsure about the advantages of hopping on early NFL betting lines, last week reminded us all.

Right away on Thursday, we were looking at the Packers as 3-point favorites. I oddly enough was on the 49ers side of that spread, but if you liked Green Bay, that was the time to pounce.

A day or two after the initial lines dropped, the Packers moved to 7-point favorites. They covered that spread, too, but the point is still there to see.

Elsewhere, the Seahawks and Bills came in with a 51 total. They would have crushed pretty much any total in week nine, but they smoked that one, and it ended up moving at almost every site.

There is risk in placing bets early, but there can also be major gains. Either way, it’s always good to get a look at the week ahead as soon as possible.

Check out the early NFL week 10 odds, and then head to our NFL picks section for more details on how to bet this week.

Indianapolis Colts vs. Tennessee Titans Odds

Colts (+2) -108
Titans (-2) -112
Over 50 -110
Under 50 -110

The Colts lost a tough one to the Ravens last week, but still have first place in the AFC South in sight. As do the Titans, who rebounded from a two-game skid last week to take over the top of the division at 6-2.

This is a slugfest for AFC South supremacy, and it’s priced like it. I don’t love the line, but if I had to pick a side, I’d go with the more trustworthy Titans.

When you factor in Indy’s defense, however, the Under feels like a pretty good bet given the fairly high total going into week 10.

Houston Texans vs. Cleveland Browns Odds

Texans (+2.5) -108
Browns (-2.5) -112
Texans to Win +125
Browns to Win -145
Over 54 -112
Under 54 -108

This looks like a tough one to gauge, as the Texans won in week nine, and are quietly turning things around (2-3 over their last five games). That doesn’t jump out, but Deshaun Watson and company were 0-4 to start the year.

Cleveland is pretty under the radar despite being 5-3, but they’re also banged up, and may not have the desired focus coming out of a bye week.

Factor in a COVID-19 situation involving quarterback Baker Mayfield, and the early bets may favor the Texans.

Does that mean you back the Texans at a discount price, or go with Cleveland as the home favorites? That’s up to the bettor.

If Mayfield ends up being out, though, this may end up being by far the best price for Houston this week.

Jacksonville Jaguars vs. Green Bay Packers Odds

Jaguars (+14) -116
Packers (-14) -104
Jaguars to Win +650
Packers to Win -910
Over 53 -110
Under 53 -110

All it took was a beatdown of the Niners in San Francisco to turn the Packers into insane two-touchdown favorites in week 10. The Jaguars are bad and Green Bay’s offense is quite good, but this spread feels rather rich.

Hunting the Jags as a potential upset special isn’t that bad of an idea, as Minnesota won at Lambeau two weeks ago.

That said, there should be points in this one, so a relatively friendly game total may be the way to seek involvement in this game.

Philadelphia Eagles vs. New York Giants Odds

Eagles (-3) -110
Giants (+3) -110
Eagles to Win -155
Giants to Win +135
Over 42 -115
Under 42 -105

Philly just beat the Giants a few weeks back, and thanks to two straight wins, are suddenly all by themselves atop the NFC East.

That kind of means nothing, but still.

The Eagles are also getting healthy, so they look like the understandable favorites here, even on the road. Their spread is pretty thin, though, so hopping on the superior Eagles feels like the best call here.

On top of that, this game total feels a little low. There’s enough offensive upside with the Eagles to get a little ambitious there.

Denver Broncos vs. Las Vegas Raiders Odds

Broncos (+4.5) -110
Raiders (-4.5) -110
Broncos to Win +185
Raiders to Win -215
Over 50.5 -110
Under 50.5 -110

Drew Lock has been bad for the majority of his last two games, but he’s found a way to rally the Broncos twice. It’d be nice if he just played a complete game – and he’ll be the first to tell you that – but bettors can’t trust Denver right now.

Las Vegas will be the safer play at home here, but the point spread keeps Denver on the board. More than anything, though, a lack of defense makes this game total (specifically the Over) the top bet to target in the early going.

Los Angeles Chargers vs. Miami Dolphins Odds

Chargers (+2.5) -108
Dolphins (-2.5) -112
Chargers to Win +125
Dolphins to Win -145
Over 50 -110
Under 50 -110

Are the Miami Dolphins for real? They sure seem to be. They’re 2-0 in the Tua Tagovailoa era, and they also happen to have a pretty good defense.

Miami is inching toward a playoff push, while a talented Chargers team simply can’t get out of their own way. The spread doesn’t interest me, but Miami to get the job done at home is worth a look.

Much like we’ve been doing all year, we can target the Over in an L.A. game, and after seeing what they’re capable of offensively last week, Miami could help get this one over a pretty tame total.

Buffalo Bills vs. Arizona Cardinals Odds

Bills (+2) -110
Cardinals (-2) -110
Bills to Win +110
Cardinals to Win -130
Over 53.5 -115
Under 53.5 -105

Both of these teams are coming off of wild finishes, and the offensive upside is out of control. I certainly respect Buffalo’s defense more, of course, seeing as they just contained Russell Wilson to a degree.

There should still be quite a bit of scoring here, with BetOnline listing this game total at a cool 53.5 to start the week. Needless to say, the top bet is probably the Over.

The doubt may lie in this total staying this low, while if you’re looking for a team to back, the surging Bills (three wins in a row) clearly offer the most value.

Seattle Seahawks vs. Los Angeles Rams Odds

Seahawks (+1) -110
Rams (-1) -110
Seahawks to Win +105
Rams to Win -125
Over 55.5 -110
Under 55.5 -110

Seattle’s offense wasn’t good enough last week, which led to the team’s second loss in the last three games. Russell Wilson’s MVP tour hit a bit of a snag, and he could have difficulty getting it back on track on the road against the Rams.

The NFC West is absurdly crowded at the moment, with this game having major ramifications on first place. I tend to favor Seattle in what is shaping up as a true pick’em, but it’ll be tough to get away from this total when you look at the possibility of a shootout.

Seattle’s defense has been laughably bad, after all.

Cincinnati Bengals vs. Pittsburgh Steelers Odds

Bengals (+9) -110
Steelers (-9) -110
Bengals to Win +340
Steelers to Win -420
Over 47 -115
Under 47 -105

The Steelers did not look great in a narrow escape in Dallas last week. Pittsburgh stayed perfect, but they appear to be inching closer to their first loss of the season.

Does it come at home against the Bengals in week 10? I doubt it, but the Bengals have a thick spread to beat, and their +340 moneyline is sublime.

Betting on Cincy at +9 feels like the right play early in the week, although the Over also looks pretty tempting.

Baltimore Ravens vs. New England Patriots Odds

Ravens (-6.5) -115
Patriots (+6.5) -105
Ravens to Win -285
Patriots to Win +240
Over 41.5 -110
Under 41.5 -110

Lamar Jackson and company haven’t made it look pretty in 2020, but they’ll head to Massachusetts with a 6-2 mark this week.

Baltimore’s defense and running game still gives them the clear edge, as they prepare to battle Cam Newton and the Pats on the road.

Bettors really can’t trust New England anymore, so this one is wide open. The only thing I like is the Over, at first glance, as 41.5 is just painfully low.

Minnesota Vikings vs. Chicago Bears Odds

Vikings (-2.5) -115
Bears (+2.5) -105
Vikings to Win -145
Bears to Win +125
Over 44.5 -110)
Under 44.5 -110

Lastly, we get an NFC North clash to close out the week, with the Vikings and Bears facing off on Monday Night Football.

Normally I’d like the Bears here, as they’re at home, and have the better defense. However, their offense has looked dreadful, and Minnesota has looked very good in two straight wins.

And really, Dalvin Cook can’t be stopped.

Minnesota feels like the target here, but the way this game sets up should make for a pretty low-scoring affair.


That does it for my early week 10 NFL betting lines breakdown. As noted in the introduction, there is real value in looking at the odds the second they drop.

There’s also risk in placing bets early in the week, but it’s up to the bettor to combine the latest analysis, odds, and news to formulate the best possible wager.

If you like the odds or analysis seen in my early NFL week 10 odds breakdown, get a jump on things and place some bets at the best football betting sites.

Noah Davis
Noah Davis

Noah Davis is one of the more diverse writers at GamblingSites.com. Like many of his colleagues, he's a huge fan of both football and basketball. But he also writes about box office records, TV show prop bets, DFS, and all kinds of other subjects.

When it comes to the NFL, Noah's favorite team is the Cleveland Browns. He enjoys cheering them on with his wife and daughter.

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