250% up to $5,000
- Offers one of the largest welcome bonuses
- Accepts many payment methods
- Bitcoin and crypto friendly
- 225+ slot games
Deposit Method



+12 More
2021 US Open Odds and Analysis for Men’s Singles

In tennis lingo, to “do a Grand Slam” means to win all four majors in one calendar year – the Australian Open, French Open, Wimbledon, and US Open.
The world no.1 Novak Djokovic has already won the first three; can he add the 2021 US Open to the list?
We will find out the answer in the next couple of weeks. The 141st edition of the tournament starts on Monday, August 30 and ends with the Men’s Singles final on Sunday, September 12.
One hundred and twenty-eight elite ATP players will gather around at the USTA Billie Jean King National Tennis Center to compete for the title. The winner will receive a $2.5 million prize, as well as 2,000 ranking points.
Obviously, that’s enough to make everyone give their best. If you’re thinking about betting on the 2021 US Open, hopefully my preview of the latest odds and top contenders will be of good use.
Let’s start with the pricing and break down the top contenders for the men’s side.
2021 ATP US Open Odds to Win
If you’re wondering who will win the men’s US Open in 2021, it makes sense to start with the guy eyeing a Grand Slam.
It’s only happened 29 times in tennis history, and it’s so hard that some of the greatest men’s tennis players haven’t been able to do it.
No one should be surprised that Djokovic is a heavy favorite to win the 2021 US Open. The odds suggest that there’s an 83.3% chance he will get ahold of the title.
However, similar was the case ahead of the 2020 tournament, but then the lineswoman fiasco happened.
Why Novak Djokovic is the #1 Favorite
“Don’t hit anyone in the throat” – this is probably one of the main items on Novak’s to-do list for the 2021 US Open.
As a reminder, the Serbian entered the 2020 tournament as a huge favorite, but then ended disqualified in the fourth round. The reason? He hit a line judge in the throat with the ball.
A year later, Djokovic is once again the #1 favorite.
Djokovic has been imperious this entire year, winning 38 matches and losing only five. The best thing is that only two of those defeats happened on the hardcourt – the kind of surface used at the US Open.
The bad news is that both of those defeats happened recently. In fact, those were the last two matches Djokovic played before this tournament.
First, he lost to Alexander Zverev in the semifinal of the Tokyo Olympics; then, he lost the bronze medal match to Pablo Carreno-Busta.
Both of those guys are among the dark horses of the 2021 US Open title. Then, there’s also Daniil Medvedev, Stefanos Tsitsipas, and a few other “Next Gen” players, as the media dubbed them.
Still, you can be sure that Novak doesn’t fear any of those players. In fact, he has a positive record against most of them, as you can see below:
- 5-3 against Daniil Medvedev
- 6-3 against Alexander Zverev
- 6-2 against Stefanos Tsitsipas
- 2-0 against Hubert Hurkacz
- 3-0 against Matteo Berrettini
- 1-0 against Jannik Sinner
- 12-0 against Milos Raonic
- 10-0 against Denis Shapovalov
The only player from the list of top 10 US Open favorites who still hasn’t lost to Djokovic is Andrey Rublev. The reason? The two have never met.
Other Men’s US Open Contenders
If you’re wondering where Djokovic’s biggest foes are – Rafael Nadal and Roger Federer – they’re not taking part in the tournament for health reasons.
Furthermore, the winner of the last season’s US Open, Dominic Thiem, has also been forced to withdraw, after suffering a wrist injury.
BREAKING: Defending champion Dominic Thiem will miss the 2021 @usopen, as well as the rest of the 2021 season due to a wrist injury.#USOpen pic.twitter.com/gNAzOOHZ5S
— Tennis Channel (@TennisChannel) August 18, 2021
It seems that the 2021 US Open will be Djokovic vs. everyone else. He’s just so much better than any other player taking part in the tournament that it would be a major surprise if he didn’t win the title.
But surprises do happen, especially when Djokovic is concerned.
Even though he’s just one step away from settling the GOAT debate in his favor, the Serbian player has taught us he can be his biggest enemy sometimes.
So, if Djokovic knocks himself out of the tournament, who will ascend to the throne?
Daniil Medvedev
Daniil Medvedev looks like the obvious choice, just behind Novak Djokovic in the ATP Rankings. In fact, he could get to the very summit of that list by winning the 2021 US Open.
Of course, only if Djokovic loses early on.
Not only is the 6’6 Russian one of the most talented players on the planet, but he’s been in pretty good form. He’s coming to New York after winning the ATP Toronto and reaching the Cincy semifinal.
Alexander Zverev
Alexander Zverev is another 6’6 player who has a good chance to win the tournament. Like Medvedev, Zverev is also in fantastic form, with all wins in the past 11 matches.
During his winning run, Zverev won the Olympic gold, as well as the title at the ATP Cincinnati. The most impressive fact about his streak is that one of those wins was the 2-1 win over Novak Djokovic in Tokyo.
Betting on the Men’s 2021 US Open
It would be crazy not to think Djokovic is going to win the title – he’s the best tennis player in the world today. Plus, he must feel very motivated ahead of his trip to New York.
On top of that, he would win his 21st major title.
Knowing that he, Nadal, and Federer, currently have 20 titles each, winning the 2021 US Open would give the Serbian an upper hand over his arch-rivals.
For Djokovic, the 2021 US Open campaign comes to this – if he wins the title, he becomes the GOAT!
Hopefully, this 2021 US Open betting preview for the men’s singles tournament helps you out. For individual matches, odds, and picks, head over to our tennis betting picks page.
- Early Odds for Week 1 in College Football (2022)The wait is finally over. Football season is here, and the Week 1 college football lines are...
- Ranking the Top 10 Richest Players in Poker HistoryWho are the richest poker players on the planet? Needless to say, hundreds of professional poker players...
- Odds and Prediction for the 2022-23 Big Bash LeagueThe 2022 Big Bash League odds have landed. The 12th edition of Australia’s beloved T20 cricket tournament...
- 7 Anime Slot Machines You Should Play Right NowJapanese anime (visual stories told with drawn animation) and Japanese manga (comic books and graphic novels illustrated...
- Early Odds for Week 1 in College Football (2022)The wait is finally over. Football season is here, and the Week 1 college football lines are...
- Ranking the Top 10 Richest Players in Poker HistoryWho are the richest poker players on the planet? Needless to say, hundreds of professional poker players...
- Odds and Prediction for the 2022-23 Big Bash LeagueThe 2022 Big Bash League odds have landed. The 12th edition of Australia’s beloved T20 cricket tournament...
- 7 Anime Slot Machines You Should Play Right NowJapanese anime (visual stories told with drawn animation) and Japanese manga (comic books and graphic novels illustrated...